Vagus Nerve Stimulation for the Treatment of Epilepsy
نویسندگان
چکیده
منابع مشابه
Vagus nerve stimulation for treatment of epilepsy in Rett syndrome.
This case series presents the outcomes of seven females with Rett syndrome and medically refractory epilepsy who were treated with adjunctive vagus nerve stimulation (VNS) therapy for a minimum of 12 months. Patients ranged in age from 1 to 14 years (median age 9 y) at the time of implantation, had experienced seizures for a median period of approximately 6 years, and had failed at least two tr...
متن کاملTreatment of epilepsy by stimulation of the vagus nerve.
We treated 14 patients with medically refractory partial seizures by stimulation of the vagus nerve in two single-blind pilot studies. Patients received stimulation through an implantable, programmable NeuroCybernetic Prosthesis, consisting of a pulse generator and a lead-electrode assembly. The mean reduction in seizure frequency after 14 to 35 months of vagal stimulation was 46.6%. Of the 14 ...
متن کاملAssessment of Vagus Nerve Stimulation for Epilepsy
Introduction and methodology. Despite a recent surge in availability of new antiepileptic medications and advances in surgical therapy for epilepsy, intractable epilepsy remains a very significant problem. At least 25 to 50% of patients with epilepsy suffer from breakthrough seizures or debilitating side effects of medications. We need a safe and effective treatment for these people, even if it...
متن کاملVagus nerve stimulation in the treatment of epilepsy.
Vagus-nerve stimulation (VNS) is now an accepted treatment for patients with refractory epilepsy. There have been many studies suggesting that VNS affects the brain in such areas as the thalamus and other limbic structures. In addition, there is some evidence that norepinephrine is important in the prophylactic antiseizure effects of VNS. The efficacy of VNS has been established for partial sei...
متن کاملReassessment: vagus nerve stimulation for epilepsy.
A July 1997 assessment of the American Academy of Neurology (AAN) Therapeutics and Technology Subcommittee reviewed vagus nerve stimulation (VNS) for epilepsy, and concluded that it was promising, but not yet established. Subsequent to that review, a second multicenter, randomized, controlled clinical trial has shown safety and efficacy of VNS for treatment of intractable partial seizures. Give...
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ژورنال
عنوان ژورنال: Neurosurgery Clinics of North America
سال: 2019
ISSN: 1042-3680
DOI: 10.1016/j.nec.2018.12.005